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HANSEN
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AGRANULOCITOSE/IND QUIM [Subject descriptor]
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Id:
13604
Author:
Ognibene, André J
Title:
Agranulocytosis due to dapsone ..-
Source:
s.l; s.n; apr. 1970. 4 p. ilus, tab.
Abstract:
Agranulocytosis developed in 16 U. S. soldiers in Vietnam who were receiving daily dapsone prophylaxis for falciparum malaria. The were eight deaths in the group. All patients had been on prophylaxis from 3 weeks to 3 months. recovery or death due to sepsis generally occurred within 9 days. The toxic effects of dapsone have resulted in a limitation in the use of dapsone for prophylaxis of falciparum malaria in U. S. troops in Vietnam.(AU).
Descriptors:
AGRANULOCITOSE/ind quim
DAPSONA/ef adv
MALARIA/prev
MEDICINA MILITAR
FATORES DE TEMPO
MEDICINA TROPICAL
ESTADOS UNIDOS
VIETNA
Limits:
HUMANO
Electronic Medium:
http://www.ilsl.br
Location:
BR191.1; 01870/s
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Id:
13273
Author:
Levine, Peter H; Weintraub, Lewis R
Title:
Pseudoleukemia during recovery from dapsone-induced agranulocytosis ..-
Source:
s.l; s.n; may 1968. 6 p. ilus, graf.
Abstract:
The case presented here illustrates how convincingly the recovery from agranulocytosis may mimic acute leukemia in both the peripheral blood and the bone marrow. The development of a leukemia-like syndrome in any patient who has been exposed to a drug known to cause agranulocytosis should raise the question of
pseudoleukemia
. Repeated bone marrow aspirations and daily observation of changes in peripheral blood parameters will help prevent needless exposure to myelossuppressive agents. The experience with this case makes mandatory an awareness of agranulocytosis as a side effect of dapsone.(AU).
Descriptors:
AGRANULOCITOSE/ind quim
AGRANULOCITOSE/diag
CONTAGEM DE CELULAS SANGUINEAS
CELULAS DA MEDULA OSSEA
DAPSONA
DIAGNOSTICO DIFERENCIAL
CONTAGEM DE LEUCOCITOS
DERMATOPATIAS/quimioter
Electronic Medium:
http://www.ilsl.br
Location:
BR191.1; 01860/s
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